Redox reaction based antibodies

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prabhuphd
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Redox reaction based antibodies

Is there any idea regarding the oxidation or reduction reaction mediated antibody? is it possible to make a antibody through this reaction? Some times the hidden antibodies are unmasked by this reaction. In this condition, is there any relationship between oxidative stress and auto antibody production in vivo?

samm
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prabhuphd wrote:

prabhuphd wrote:

Is there any idea regarding the oxidation or reduction reaction mediated antibody? is it possible to make a antibody through this reaction? Some times the hidden antibodies are unmasked by this reaction. In this condition, is there any relationship between oxidative stress and auto antibody production in vivo?

 
Superoxide and peroxide radicals can affect protein folding and conformation, and this can lead to new Abs and even autoantibody generation. I remember reading a minireview on this topic sometime back - will try to dig up the ref.