A new model of polygenic obesity and obesity-induced diabetes

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Monu
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A new model of polygenic obesity and obesity-induced diabetes

A new mouse strain that may be used as a model of polygenic obesity and obesity-induced diabetes (diabesity) and is now available with The Jackson Laboratory.
This lab mice is recombinant congenic strain developed at The Jackson Laboratory to model human obesity-induced Type 2 diabetes and also Metabolic Syndrome. Type 2 diabetes in males of this strain results from polygenic interactions producing a moderate obesity rather than the massive obesity elicited by mutations in the leptin/leptin receptor axis. One can find the details at their website, http://jaxmice.jax.org/strain/004456