Dose accumulation.

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msvnathan
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Dose accumulation.

How to calculate how much compound (environmental contaminant) accumulated in animal based on its literature value by theoritically ie for example, if the value of environmental contaminant in water is given whether it can be extrapolated to animal model accumulation? my doubt if the animal is taking certain volume of water based on that it can be calculated. any calculation model is there for this?

Thank you