GLIMMER - A Tool to identify the coding regions in Microbial DNA

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vadivelperumal
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GLIMMER - A Tool to identify the coding regions in Microbial DNA

GLIMMER

Glimmer is a system for finding genes in microbial DNA, especially the genomes of bacteria, archaea, and viruses. Glimmer (Gene Locator and Interpolated Markov ModelER) uses interpolated Markov models (IMMs) to identify the coding regions and distinguish them from noncoding DNA. The IMM approach, described a Nucleic Acids Research paper on Glimmer 1.0 (http://www.cbcb.umd.edu/papers/glimmer-nar.pdf) and in a subsequent paper on Glimmer 2.0 (http://www.cbcb.umd.edu/papers/glimmer2.pdf) , uses a combination of Markov models from 1st through 8th-order, weighting each model according to its predictive power. Glimmer uses 3-periodic nonhomogenous Markov models in its IMMs.

FURTHER DETAILS:-

http://www.cbcb.umd.edu/software/glimmer/