Most people use internal solution with Cs+ as the main ion to record minis. Can minis be recorded with KCl instead and TTX in the bath? If not, why?
You will certainly see minis in a KCl internal solution. But by severely reducing K+ efflux with the Cs internal solution, you will have better voltage control over a greater region of your neuron. there will be less attenuation of minis recorded from more distal sites with the Cs solution.