Perkin Elmer ELAN 9000 ICP-MS and Cetac ASX-520 Autosampler In attempts to upgrade from windows XP to Windows 7 and upgrade ELAN software to 3.5, connection to my CETAC autosampler was lost.The computer could see the autosampler, it would not control it and thus it was useless. The following is an excerpt from communication with a PE tech that completely fixed my issue. Since it was stated that the PC was swapped my bet would be there was a mistake following the PC instructions. Many users don’t perform the steps in the instructions that comes after the GPIB driver about configuring the driver including setting up the autosampler device, in particular the step where the device name for address 14 is changed to AUSMP gets missed. So the Elan software is looking for AUSMP, the driver only has DEV14 (the default name) and communication does not occur. The Elan itself communicates on DEV1 and the name does not need to be changed which also causes people to skip over the name changing step for DEV7 and DEV14. The device setup and GPIB communication settings begin on page 36 of the attached document. I also have one more possible long shot question. Was this autosampler used with the Elan on the previous PC and autosampler or did it come from a different instrument? The Cetac autosamplers have different firmware for different manufactures so an ASX520HS that was used on Thermo instrument would not talk to a PerkinElmer instrument until the firmware is changed to the appropriate version.