Hello
Acetylcystein
In USP : Loss on drying : Dry it at a pressure of about 50 mm of mercuric at 70 C for 4 hours: it loses not more than 1.0% of it weight
I have only hot air oven / don't have vacuum oven.
I can use hot air oven intead vacuum oven ????
If I can What status as pressure of about 50 mm of mercuric at 70 C
help me please , thank you very much
The drying is performed at reduced pressure so that the temperature can also be reduced. The compound may be unstable at 100 C. Drying in a hot air oven may not give the same result.
If you want to do a USP test, then this change would not be acceptable.