Applications and features of Subtractive cDNA Library

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wendy wilson
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Applications and features of Subtractive cDNA Library

A subtractive cDNA library is a collection of cDNA clones which is rare and likely to be poorly expressed. Subtractive cDNA libraries are produced using a proprietary technique which relies on the removal of dsDNA formed by hybridization between a control and test sample, thus eliminating cDNAs of similar abundance and retaining the transcripts which are differentially expressed or variable in sequence.