LAM PCR

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wendy wilson
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LAM PCR

LAM PCR (Linear - amplification mediated PCR) is a technology which is used for identifying and characterizing unknown flanking DNA adjacent to known DNA of any origin. More specifically, LAM-PCR has been developed to localize viral vector integration sites (IS) within the host genome [1, 2]. Genetic elements like retroviruses or transposons integrate their genome into the host genome in a (semi-) random manner [3-6].