Scientist Solutions: International Life Science Community By Scientists For Scientists
    
Home » Protocols » In Vivo Fluorescence Imaging of Tumor Proliferation Using Pre-labeled Cancer Cells and a Targeted Probe
Thanks to our sponsors who make this site possible
Search protocols by keyword   or   Post a new protocol
Next Protocol >
 Link To Us    Bookmark Us     Chinese
Protocol for

In Vivo Fluorescence Imaging of Tumor Proliferation Using Pre-labeled Cancer Cells and a Targeted Probe

Would you like to save this topic, event, protocol or job so you can find it again easily?

Just click the "Save to My Lab Drawer" link and the item will be saved in the My Lab Drawer section of your bench space.

Available to members only. Please log in or register for your free account now.

Close Window 
Abstract or Description:
View Printable Version

Optical molecular imaging techniques have emerged as valuable tools for pre-clinical oncology research in mouse models of cancer.1-5 Diseased tissues and cells are typically detected during in vivo fluorescence imaging by one of three means: (1) near-infrared (NIR) injectable probes that are either targeted1,3,4 or activated by2,6 tumor cells, (2) tumor cells that are exogenously labeled in culture with NIR dyes7 and subsequently injected in vivo, or (3) cell lines that have been genetically modified, typically through viral vectors, to express fluorescent protein reporters that allow in vivo detection.5,8 We demonstrate here an imaging experiment that merges two of these strategies. Exogenously labeled tumor cells were implanted and subsequently detected by an injectable, targeted probe with a different emission wavelength.

Citation:
Attachments: No Attachments
Posted By: Carestream Health on 1/10/2012 8:35:01 AM
Comments
Add Comment
       

Board Rules | advertise | Privacy

Copyright © 2004-2012 Scientist Solutions, All Rights Reserved.
Resources from NCBI used on this site.