Protocol for: Purification of ?-2-macroglobulin and the construction of immunogenic ?-2-macroglobulin""?peptide complexes for use as cancer vaccines
Abstract or Description:
A simple method for
purification of immunogenic ?-2-macroglobulin from murine
serum is described. Also described is a method for creating ?-2-macroglobulin""?
antigen complexes using purified ?-2-macroglobulin and
peptides derived from
tumor cell lysates. The application of such ?-2-macroglobulin""?
antigen complexes for eliciting
cancer immunity is discussed.
Citation: http://dx.doi.org/10.1016/S1046-2023(03)00184-1
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