Description of event:
B Cell Development and Function
Scientific Organizers: Max D. Cooper, Andrea Cerutti and Carola G. Vinuesa
February 10—15, 2013
Keystone Resort, Keystone, Colorado, USA
Meeting Summary
This meeting will provide an overview of the most recent advances in the
biology of
B cells. In addition to covering the function of
B cells under steady-state conditions and
infection, the meeting will provide an update on the alterations of
B cells in
autoimmunity, leukemia and lymphoma. The mechanisms by which
B cells crosstalk with different components of the innate and adaptive immune systems and the contribution of distinct
B cell subsets to systemic and mucosal
immunity remain unclear, particularly in humans. This meeting has the following specific aims: 1) to define the factors involved in
B cell lineage specification and reprogramming; 2) to elucidate the evolution and mechanisms of the processes underpinning
antibody gene diversification; 3) to better understand the
B cell pathways required for systemic and mucosal
antibody responses against
T cell-dependent and
T cell-independent antigens; 4) to clarify the mechanisms by which
antibodies provide protection against
HIV; 5) to broaden our understanding of the molecular alterations associated with
autoimmune and neoplastic
B cell disorders; and 6) to provide an interactive forum to involve early stage investigators and highlight their discoveries. By addressing these problems, this meeting will not only generate new knowledge on the
biology of
B cells in health and
disease states, but it will also provide a framework for investigators and clinicians to generate new ideas, initiate new collaborations, and eventually introduce changes in
clinical practice. In addition, this meeting will provide a unique opportunity to “take a closer look” at
B cells by linking experts in B
cell biology with experts in
stem cell biology, comparative
immunology,
molecular biology, and
in vivo imaging. Additional opportunities for interdisciplinary
interactions will be significantly enhanced by the concurrent meeting on
HIV Vaccines, which will share a keynote session and two plenary sessions with this meeting.
General information
Keystone Resort, only 90 minutes from Denver International Airport, is a year round comprehensive resort spanning seven miles along the Snake River and nestled in the White River National Forest. Keystone offers extensive experiences for conferees and their families and guests, including over 3,000 acres for skiing and riding, tubing hill, Nordic Center for snow shoeing, cross country and skate skiing, a 5 acre lake for ice skating, and horse drawn sleigh rides. Keystone Lodge has a renovated spa with ten treatment rooms, relaxation room, men's and ladies spa locker rooms. There are numerous heated swimming pools and hot tubs for relaxing. Choose from over twenty five restaurants for casual and fine dining; and two of the fine dining restaurants are AAA Four Diamond and Zagat rated. A complimentary intra-resort shuttle provides access to all attractions and activities.
Location
Keystone Resort
21996 US Highway 6
PO Box 38
Keystone, Colorado 80435-0038
USA
Travel inforamtion
Conference Center Notes: The Conference Center is separate from the guest rooms at Keystone Resort. Use of the free resort shuttle or walking outside will be necessary. Clothes and shoes appropriate to winter conditions are necessary.
Shuttle Information: Keystone Resort has a complimentary shuttle for transportation in and around the resort.
Contact us:
Keystone Symposia
160 U.S. Highway 6, Suite 200
PO Box 1630
Silverthorne, CO 80498