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Free Webinar from The Jackson Laboratory Optimizing Preclinical Models for Drug Discovery: Lessons Learned from Spinal Muscular Atrophy and other Neurodegenerative Diseases
Aug 23, 2012 - Aug 23, 2012
Event Type: Webinar
Registration Deadline: Aug 21, 2012
Abstract Submission Deadline: None
Description of event:
Free Webinar from The Jackson Laboratory
Optimizing Preclinical Models for Drug Discovery: Lessons Learned from Spinal Muscular Atrophy and other Neurodegenerative Diseases
August 23, 1:00 PM (ET in US)
Despite an understanding of the molecular mechanisms of many neurodegenerative diseases, such as spinal muscular atrophy (SMA), Friedrich’s ataxia, and amyotrophic lateral sclerosis (ALS), the lag in developing preclinical mouse models has stymied preclinical drug discovery trials. Learn how The Jackson Laboratory’s Rare and Orphan Disease Center is partnering with rare disease foundations, and advocacy groups to develop, validate, and distribute preclinical models and resources to advance preclinical research in these and other neurodegenerative diseases. Join Jackson Laboratory scientists Cathleen Lutz, Ph.D., and Sheri Kuslak-Meyer, Ph.D., as they discuss the following topics:
· The evolution of SMA mouse models
· Emerging mouse models that are providing vital insights into therapeutic treatment of SMA
· The key roles of genetic background and phenotypic standardization in providing consistent preclinical models
· Using available data and resources to accelerate pre-clinical research of SMA, Friedrich’s ataxia, ALS and other rare yet devastating human diseases
Register for this free webinar today at www.jax.org//jaxmice/news/2012/neuroWebinarAugust.