Description of event:
Noncoding RNAs in Development and Cancer
Scientific Organizers: Joshua T. Mendell, Phillip A. Sharp, Judy Lieberman and Howard Y. Chang
January 20—25, 2013
Fairmont Hotel Vancouver, Vancouver, British Columbia, Canada
Meeting Summary
A recurrent principle in
cancer biology is the co-option of
pathways that function during development to promote aberrant
tumor cell behavior. This principle clearly applies to the roles of noncoding RNAs in
cancer. Examples of noncoding RNAs that modify
tumor phenotypes include the
microRNA (
miRNA) let-7, a key regulator of developmental timing in C. elegans, and the miR-17-92 cluster, which conducts essential regulatory functions during
mammalian development. However, we currently have only a rudimentary understanding of how diverse classes of noncoding RNAs function in physiologic and pathophysiologic states. This meeting will bring together experts focused on the roles of noncoding RNAs in development and
cancer with the broad goals of: 1) Illuminating new connections between developmental and
cancer pathways controlled by miRNAs and long noncoding RNAs; 2) Uncovering novel mechanisms by which developmental and
cancer pathways influence noncoding
RNA processing and activity; 3) Revealing the molecular mechanisms through which miRNAs and long noncoding RNAs function in these
pathways; and 4) Highlighting how our understanding of noncoding
RNA-regulated
pathways can be applied in the development of novel
therapeutic strategies for
cancer and perhaps other diseases. To accomplish these goals, this meeting will bring together experts from disparate fields ranging from organismal-level developmental and
cancer biology to biochemical and molecular studies of
RNA function to share their newest
data and ideas. It is anticipated that the diverse views, approaches and results presented by participants will foster new lines of investigation and collaborations which will be critical to dissect the myriad functions of noncoding RNAs in health and
disease.
General information:
The Fairmont Hotel Vancouver is a beautiful and historic landmark in downtown Vancouver surrounded by the majestic North Coast Mountains. The hotel offers a complimentary fitness facility, spa, (charges apply), indoor swimming pool, hot tub, and two restaurants. Within a few minutes' walk from the hotel is Robson Street for superb shopping and dining options. Other highly suggested attractions of this oceanfront city are Stanley Park, The Vancouver Art Museum, and Granville Island. Three ski areas are only a short drive away, offering alpine, cross-country, and snowboarding as well as snowshoeing, ice-skating, and sleigh rides, (weather permitting). Complimentary ski shuttles will be available. Vancouver provides all the options of a resort combined with a cosmopolitan city appeal.
Conference Location:
Fairmont Hotel Vancouver
900 West Georgia Street
Vancouver, British Columbia V6C 2W6
Canada
Travel information:
Conference Center Notes: The Conference Center is located within the same building as the guest rooms. It is not necessary to walk outdoors to reach the Conference Center.
Shuttle Information: Vancouver has many forms of transportation to help conferees explore the area. Taxis are readily available;
water taxis can take conferees to Granville Island and others areas of exploration. Ask the concierge at the hotel for more details.
Contact us
Keystone Symposia
160 U.S. Highway 6, Suite 200
PO Box 1630
Silverthorne, CO 80498