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Modeling Human Disease in Immunodeficient Mice
Jun 21, 2012 - Jun 21, 2012
Event Type: Webinar
Registration Deadline: Jun 19, 2012
Abstract Submission Deadline: None
Description of event:
Webinar: Modeling Human Disease in Immunodeficient Mice
June 21, 1:00 PM (ET in US)
Immunodeficient mice have become powerful tools for modeling human disease. In this webinar, JAX technical information scientists Peter Kelmenson and Brian Soper will highlight currently available models and important considerations for choosing the most appropriate model for your research. They will discuss the following topics:
· The mechanistic etiology of immunodeficiency in common mouse models
· Benefits and limitations of using nude, scid, and Rag1-null mice for your research
· Recent studies and advantages of using the most versatile and powerful immune deficient model, the NOD-scid gamma (NSG)
· Preservation of primary human tumors in immunodeficient mice, including long-term maintenance of the tumor microenvironment and its associated immune cells
· Model considerations for generating a "humanized" immune system
Register for this free webinar today at www.jax.org/jaxmice/news/2012/immunoWebinarJune.