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eliassi |
| Member since: |
Jul 21, 2005 |
| From: |
Rehovot, Israel |
| Status: |
Frog Egg |
| My points: |
33
what's this
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| Name: |
[Privacy] |
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As a manager of new technologies and assay development and Senior scientist as well as projects leader in the Ubiquitin field
I'm Working on various projects involving the Ubiquitin re-cycling system for Amino Acids (in association with big Pharma companies in ISRAEL and abroad).
My wrok involves planning of milestones in projects, building, adaptation and validation of ISO compatible protocols. Fine tuning and optimization of assay terms, Quality assurance and Quality control (QA/QC), developing SOPs based on GLP& amp; GMP (controlled documents) and adaptation to robotics unit ( HTS). Rich experience in QC, QA, development of protocols and SOPs supporting GMP & amp; GLP.
Development and delivery of protocols to HTS group in order to search and trace compounds, among known compound libraries, that inhibit specifically target proteins. Those compounds were checked to be effective, non cyto-toxic (in cell assays as well as animal studies). The work includes qualification of HTS and R& amp;D teams to work, based on SOPs. Various Enzyme studies (define K m, V 0, V max, and K I).
1. Zusman, T., O. Gohar, I. Eliassi, Y. Avivi, E. Lisansky, C. Sautès, J. Even, C. Bonnerot, W.H. Fridman, I.P. Witz and M. Ran, The Murine Fc-Gamma (Fcγ) Receptor type II B1 is a Tumorigenicity-Enhancing Factor in Polyoma- virus-Transformed 3T3 cells. Int. J. Cancer, 1996. 65: 221-229.
2. Ran, M., A. Ben-Baruch Langer, I. Eliassi, O. Gohar, B. Gonen, S. Gradsztajn, W.H. Fridman, J.L. Teillaud and I.P. Witz, Possibilities of Interference with the Immune System of tumor bearers by Non-Lymphoid FcγRII Expressing Tumor cells. Immunobiol., 1992. 185:415-425.
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